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  • Physiologic analyzers designed for non-invasive measurement of cutaneous fluorescence over time for evaluating cutaneous microcirculation. These devices typically consist of a UV light source (e.g. UV LED), a quartz window, excitation and emission filters, a detector (usually photodiode), an automatic occlusion module with cuff, an arm positioner, and an electronic control unit. Flow-mediated skin fluorescence analyzers are typically used to assess cutaneous microcirculation by measuring skin fluorescence intensity as a function of time following the blockage and release of blood flow to the measured tissue (e.g., forearm skin fluorescence measurements following brachial artery occlusion).
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