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A coded value specifying the prefix or suffix, used in conjunction with AJCC clinical TNM designations, that denotes special circumstances that may affect the staging and analysis of the data and is based on the pathologic T, N, and M values after completion of surgical treatment. EXAMPLE(S): For the U.S. National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) program: 0 = None 1 = E (Extranodal, lymphomas only) 2 = S (Spleen, lymphomas only) 3 = M (Multiple primary tumors in a single site) 4 = Y (Classification during or after initial multimodality therapy)-pathologic staging only 5 = E & S (Extranodal and spleen, lymphomas only) 6 = M & Y (Multiple primary tumors and initial multimodality therapy) 9 = Unknown, not stated in patient record OTHER NAME(S): NOTE(S): The descriptors are adjuncts to and do not change the stage group.
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