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ABSTRACT Objective: To compare the efficacy of titanium mesh to autologous bone grafting in cranioplasty and assessing complications like seroma and abscess formations and subjective measures of pain Study Design: Comparative cross-sectional study Place and Duration of Study: Neurosurgery department, CMH Rawalpindi, from Aug 2017 to Dec 2018 Methodology: Twenty patients(Women=12, Men=8) were randomly assigned to Titanium Mesh(TM) group and 20 patients(Women=7, Men=13) to Autologous Bone Graft(ABG) group All were subjected to cranioplasty using Titenium Mesh and Autologous Bone Graft procedures to assess cranial seroma and abscess formation and pain Results: Comparison of pain on day 3 showed seven(35%) patients in titenium mesh group experienced pain compared to 14(70%) patients in the autologous bone graft group, which was statistically significant(p0 001) Similarly, a comparison on day 7, revealed that pain in the titenium mesh group reduced to five(25%) patients compared to 11 patients(55%) in the autologous bone graft group, which again was statistically significant(p0 001) Four(20%) patients in titenium mesh group and 7(35%) patients in autologous bone graft group developed seroma on day 3 and the difference was significant(p0 001) Two(10%) patients in titenium mesh group and five(25%) patients in autologous bone graft group developed abscess, which was significantly different(p0 001) Conclusion: Cranioplasty using titenium mesh is better than autologous bone graft because complications like seroma, abscess and pain are attenuated in surgical cohorts
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