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In this commentary, we shed light on the role of the mammalian target of rapamycin (mTOR) pathway in viral infections. The mTOR pathway has been demonstrated to be modulated in numerous RNA viruses. Frequently, inhibiting mTOR results in suppression of virus growth and replication. Recent evidence points towards modulation of mTOR in SARS-Cov2 infection. We discuss the current literature on mTOR in SARS-Cov2 and highlight evidence in support of a role for mTOR inhibitors in the treatment of COVID-19. This article is protected by copyright. All rights reserved.
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Journal_of_medical_virology
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mTOR inhibition in COVID-19: A commentary and review of efficacy in RNA viruses.
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