PropertyValue
?:abstract
  • A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently spreading across many countries globally. Here, we show that a TMPRSS2-expressing VeroE6 cell line is highly susceptible to SARS-CoV-2 infection, making it useful for isolating and propagating SARS-CoV-2. Our results reveal that, in common with SARS- and Middle East respiratory syndrome-CoV, SARS-CoV-2 infection is enhanced by TMPRSS2.
?:creator
?:doi
?:doi
  • 10.1073/pnas.2002589117
?:journal
  • Proc_Natl_Acad_Sci_U_S_A
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/8b7be2d10a60bd2f6941affc3bddce8773c3ac8c.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7132130.xml.json
?:pmcid
?:pmid
?:pmid
  • 32165541.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
?:type
?:year
  • 2020-03-31

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