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?:abstract
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BACKGROUND: Asthmatics and COPD patients have more severe outcomes with viral infections than people without obstructive disease OBJECTIVE: To evaluate if obstructive diseases are risk factors for ICU stay and death due to COVID19 METHODS: We collected data from the electronic medical record from 596 adult patients hospitalized in University hospital of Liege between 18(th) of March and 17th of April 2020 for SARS-CoV2 infection We classified patients in three groups according to the underlying respiratory disease, present prior to COVID19 pandemics RESULTS: Among patients requiring hospitalization for COVID19, asthma and COPD accounted for 9 6% and 7 7% respectively The proportions of asthmatics, COPD and patients without obstructive airway disease hospitalized in ICU were 17 5%, 19 6% and 14% respectively One third of COPD patients died during hospitalization while only 7 0% of asthmatics and 13 6% of patients without airway obstruction died due to SARS-CoV2 The multivariate analysis showed that asthma, COPD, ICS treatment and OCS treatment were not independent risk factors for ICU admission or death Male gender (OR:1 9;95%CI: 1 1 to 3 2) and obesity (OR:8 5;95%CI: 5 1 to 14 1) were predictors of ICU admission while male gender (OR1 9;95%CI: 1 1-3 2), older age (OR:1 9;95%CI: 1 6-2 3), cardiopathy (OR: 1 8;95%CI: 1 1-3 1) and immunosuppressive diseases (OR: 3 6;95%CI: 1 5-8 4) were independent predictors of death CONCLUSION: Asthma and COPD are not risk factors for ICU admission and death related to SARS-CoV2 infection
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