hzoxphhz

Property	Value
?:abstract	COVID-19 pandemic leads to health challenges globally, and its diverse aspects need to be uncovered Multi-organ injuries have been reported by describing potential SARS-CoV-2 entrance routes: ACE2 and TMPRSS2 Since these cell surface receptors\' expression has been disclosed within the male reproductive system, its susceptibility to being infected by SARS-CoV-2 has been summarised through this literature review Expression of ACE2 and TMPRSS2 at RNA or protein level has been reported across various investigations indicates that the male genitalia potentially is vulnerable to SARS-CoV-2 infection Presence of SARS-CoV-2 within semen samples and following direct viral damage, secondary inflammatory response causing orchitis or testicular discomfort and finally the amount of viral load leading testicular damage and immune response activation are among probable underlying mechanisms Therefore, genital examination and laboratory tests should be considered to address the male reproductive tract complications and fertility issues COVID-19 pandemic leads to health challenges globally, and its diverse aspects need to be uncovered. Multi-organ injuries have been reported by describing potential SARS-CoV-2 entrance routes: ACE2 and TMPRSS2. Since these cell surface receptors\' expression has been disclosed within the male reproductive system, its susceptibility to being infected by SARS-CoV-2 has been summarised through this literature review. Expression of ACE2 and TMPRSS2 at RNA or protein level has been reported across various investigations indicates that the male genitalia potentially is vulnerable to SARS-CoV-2 infection. Presence of SARS-CoV-2 within semen samples and following direct viral damage, secondary inflammatory response causing orchitis or testicular discomfort and finally the amount of viral load leading testicular damage and immune response activation are among probable underlying mechanisms. Therefore, genital examination and laboratory tests should be considered to address the male reproductive tract complications and fertility issues.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C0009566> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C0021359> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C0026771> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C0027627> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C0035668> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C1155266> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C1336641> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C1422064> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C2364135> <https://research.tib.eu/covid-19/entity/hzoxphhz_hasAnnotation_C5203676>
?:creator	<https://research.tib.eu/covid-19/entity/Sheikhzadeh_Hesari%2C_F.%3B_Hosseinzadeh%2C_S._S.%3B_Asl_Monadi_Sardroud%2C_M._A.> <https://research.tib.eu/covid-19/entity/Sheikhzadeh_Hesari%2C_Farzam%3B_Hosseinzadeh%2C_Seyedeh_Shaghayegh%3B_Asl_Monadi_Sardroud%2C_Mohammad_Ali>
?:journal	Andrologia
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/hzoxphhz_HAS_C0029191_COEXISTS_WITH_C5203676>
?:source	WHO
?:title	Review of COVID-19 and male genital tract
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#1066606 #944619
?:year	2020 2021

Property

Value

?:abstract

COVID-19 pandemic leads to health challenges globally, and its diverse aspects need to be uncovered Multi-organ injuries have been reported by describing potential SARS-CoV-2 entrance routes: ACE2 and TMPRSS2 Since these cell surface receptors\' expression has been disclosed within the male reproductive system, its susceptibility to being infected by SARS-CoV-2 has been summarised through this literature review Expression of ACE2 and TMPRSS2 at RNA or protein level has been reported across various investigations indicates that the male genitalia potentially is vulnerable to SARS-CoV-2 infection Presence of SARS-CoV-2 within semen samples and following direct viral damage, secondary inflammatory response causing orchitis or testicular discomfort and finally the amount of viral load leading testicular damage and immune response activation are among probable underlying mechanisms Therefore, genital examination and laboratory tests should be considered to address the male reproductive tract complications and fertility issues
COVID-19 pandemic leads to health challenges globally, and its diverse aspects need to be uncovered. Multi-organ injuries have been reported by describing potential SARS-CoV-2 entrance routes: ACE2 and TMPRSS2. Since these cell surface receptors\' expression has been disclosed within the male reproductive system, its susceptibility to being infected by SARS-CoV-2 has been summarised through this literature review. Expression of ACE2 and TMPRSS2 at RNA or protein level has been reported across various investigations indicates that the male genitalia potentially is vulnerable to SARS-CoV-2 infection. Presence of SARS-CoV-2 within semen samples and following direct viral damage, secondary inflammatory response causing orchitis or testicular discomfort and finally the amount of viral load leading testicular damage and immune response activation are among probable underlying mechanisms. Therefore, genital examination and laboratory tests should be considered to address the male reproductive tract complications and fertility issues.

is ?:annotates of