PropertyValue
?:abstract
  • Candida-associated denture stomatitis (CADS) is a fungal infection affecting 60–65% of denture wearers. Its etiology is complex and multifactorial and often associated with host immunodeficiency. Evidence exists that vitamin D has potential immunomodulatory and anti-inflammatory effects. The aim of this case–control study was to assess the association between vitamin D levels and CADS. The study included 32 complete denture wearers with CADS and 32 sex- and age-matched complete denture wearers without CADS. The patients were clinically examined, and the severity of denture stomatitis was assessed according to Newton’s classification scale. The serum vitamin D level was determined via the use of an electrochemiluminescence assay. The vitamin D level in the CADS group and control group was 54.68 ± 17.07 and 56.82 ± 17.75 nmol/L, respectively. There was no significant difference between the groups (p = 0.622). Univariate logistic regression analysis showed that the presence of CADS was not associated with hypovitaminosis D (odds ratio (OR) = 1.44; 95% confidence interval (CI) = 0.37–5.54). It can be concluded that vitamin D is not associated with CADS and does not play a significant role in host susceptibility to CADS. This finding suggests that vitamin D screening is not indicated routinely in patients with Candida-associated denture stomatitis.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.3390/dj8040121
?:journal
  • Dent_J_(Basel)
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/67b0416def3470fc76a748fc0ab59da890353030.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7712357.xml.json
?:pmcid
?:pmid
?:pmid
  • 33096916.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Medline; PMC
?:title
  • Association between Vitamin D and Candida-Associated Denture Stomatitis
?:type
?:year
  • 2020-10-21

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