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The Dandy-Walker malformation complex refers to a group of congenital central nervous system malformations that primarily involve the cerebellum and adjacent tissues This malformation consists of complete or partial agenesis of the cerebellar vermis, cystic malformation of the fourth ventricle and an enlargement of the caudal fossa In some cases, substantial enlargement of the caudal fossa is not observed and is referred to as Dandy-Walker variant To the author\'s knowledge this kind of malformation has not been reported yet in cats A 8-month-old male Domestic Shorthair cat was referred for an uncoordinated gait seen by the owners since birth General physical examination was unremarkable Neurological examination revealed generalized ataxia with hypermetria of all four limbs, wide-based standing, and intermittent intention head tremors Neurological examination was consistent with a cerebellar lesion Hematology, full biochemistry and FeLV/FIV serology did not reveal abnormalities MRI sequences of the brain showed a large retrocerebellar fluid accumulation associated with an enlarged fourth ventricle These findings were associated with cerebellar hypoplasia and partial atrophy/absence of the caudal portion of cerebellar vermis CSF analysis was performed and was unremarkable PCR analysis of Toxoplasma and Coronavirus was negative in CSF After 3 months of diagnosis, clinical signs were similar with a good quality of life Similar MRI findings have been reported in Dandy-Walker malformation in dogs or inferior cerebellar hypoplasia in purebred Eurasier dogs
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Journal_of_Veterinary_Internal_Medicine
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Magnetic resonance imaging diagnosis of Dandywalker variant in a cat
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