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BACKGROUND The COVID-19 pandemic is stressing healthcare services to an unprecedented extent. There is anecdotal evidence of reduction in organ donation and transplantation (ODT) activity across the world. METHODS The weekly organ donation and liver transplant numbers over a 3-month period (17th Feb 2020 till 17th May 2020) for the USA, UK and India were compared to their previous year\'s activity. Liver transplant activity in 6 centers from these countries with varying local COVID-19 caseload was also compared. RESULTS The COVID-19 pandemic has led to a significant contraction in organ donation and liver transplantation in all 3 countries. Peak reduction ranged from 25% in the USA to over 80% in the UK and India. The reduction was different for deceased donor and living donor liver transplantation and varied between centers within a country. There was early evidence of recovery of deceased donation in the USA and UK and resumption of living donor liver transplantation activity in India towards the end of the study period. A number of policy changes were undertaken at national and transplant center levels to ensure safe transplantation despite significant redirection of resources to combat the pandemic. CONCLUSIONS There was a substantial reduction in organ donation and liver transplantation activity across the 3 countries with signs of recovery towards the end of the study period. Multiple factors including COVID-19 severity, stress on resources and influence of regulatory agencies and local factors are responsible for the reduction and recovery.
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10.1097/tp.0000000000003416
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Trinational Study Exploring the Early Impact of the COVID-19 Pandemic on Organ Donation and Liver Transplantation at National and Unit Levels.
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