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?:abstract
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COVID-19 is a new disease with many undescribed clinical manifestations. We report herein a case of severe immune thrombocytopenic purpura (ITP) in a critical COVID-19 patient. A patient presented a severe episode of immune thrombocytopenia (< 10 × 10(9)/L) 20 days after admission for a critical COVID-19. This thrombocytopenia was associated with a life-threatening bleeding. Response to first-line therapies was delayed as it took up to 13 days after initiation of intravenous immunoglobulin and high-dose dexamethasone to observe an increase in platelet count. COVID-19 may be associated with late presenting severe ITP. Such ITP may also be relatively resistant to first-line agents. Hematological manifestations of COVID-19, such as the ones associated with life-threatening bleeding, must be recognized.
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?:doi
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10.1007/s12185-020-02931-9
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document_parses/pdf_json/422bcb65765b4922c61002d87be1d0ffe88c1ba2.json
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document_parses/pmc_json/PMC7327458.xml.json
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?:title
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Severe immune thrombocytopenic purpura in critical COVID-19
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