PropertyValue
?:abstract
  • Peptidyl mono-fluoromethyl ketones (FMKs) are a class of biologically active molecules that show potential as both protease inhibitors for the treatment of a range of diseases and as chemical probes for the interrogation of cellular processes. This review describes the current solid- and solution-phase routes employed for the synthesis of peptidyl mono-FMKs. In addition, it provides a brief overview of some of the key applications of FMKs in the fields of chemical biology and medicinal chemistry.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.3390/molecules25235601
?:journal
  • Molecules
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/cde94bda867d84bb046e61bff0d755eb4c98f66d.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7730879.xml.json
?:pmcid
?:pmid
?:pmid
  • 33260551.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Current Synthetic Routes to Peptidyl Mono-Fluoromethyl Ketones (FMKs) and Their Applications
?:type
?:year
  • 2020-11-28

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