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?:abstract
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Endotracheal intubation is an independent risk factor for respiratory infectious diseases We conducted a retrospective study in 12 cases with COVID-19 who underwent endotracheal intubation at ICU of the Guangzhou eighth hospital from January 20 to February 10, 2020 The intubation procedure, anesthetic regimen, and complication were collected and analyzed The 9 healthcare workers who involved in intubation received virus nucleic acid test and 14 days temperature monitoring All 12 patients were successfully intubated under the guidance of bronchoscope, without any complications Midazolam, Propofol and Morphine or fentanyl were used for sedation and analgesia, avoiding patients cough and agitated during the procedure The 9 healthcare workers were protected under the Personal Protective Equipment(PPE) with positive pressure protective hood The detection of oropharyngeal swab virus nucleic acid were negative in all 9 healthcare workers, none of them had fever or any respiratory symptoms The PPE with positive pressure protective hood should be needed to perform bronchoscope-guided endotracheal intubation in patients with COVID-19, it could strengthen to protect healthcare workers from virus exposure Since December 2019, a cluster of patients have been diagnosed to be infected with 2019 novel coronavirus (2019-nCoV) in Wuhan, China The epidemic has been spreading to other areas of the country and abroad A few cases have progressed rapidly to acute respiratory distress syndrome and/or multiple organ function failure The epidemiological survey has indicated that the general population is susceptible to 2019-nCoV A total of 14 children (6 months to 14 years of age, including 5 cases in Wuhan) have been confirmed to be infected with 2019-nCoV in China so far In order to further standardize and enhance the clinical management of 2019-nCoV infection in children, reduce the incidence, and decrease the number of severe cases, we have formulated this diagnosis and treatment recommendation according to the recent information at home and abroad
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