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?:abstract
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The arrival of novel health crisis by a novel member of coronavirus group named as SARS-CoV-2 by WHO took the whole world in global emergency by affecting 206 countries. The virus infects 205 countries with 86,839,226 confirmed cases, 61,565,949 recoveries and 1,876,243 deaths as on 6th January 2021. Evidences pointed out the fact that virus might first originated in bats in China and it takes only two months to cover almost every country of the world. SARS-CoV-2 belongs to Beta coronavirus and is enveloped, positive sense and single stranded RNA virus. The treatment would be difficult as SARS-CoV-2 is an RNA virus and thus the mutation rate is higher in comparison to DNA viruses. The virus infection also leads to generation of effective protective immune response of TNF, IL-1β, IL-6, IL-8, G-CSF and GM-CSF etc. that may help in virus elimination. The speed of the global spread of the current pandemic is of major concern and it creates a significant threat to economic and human health. In India, the infection spreads with an infection and fatality rate of the disease are 1.7 and 2.8% respectively. By this review we want to emphasize the actual situation and major factors associated with COVID-19 pandemic, its significance, destructions, important findings, treatments and preventive measures taken by all nations to provide better cure without having much loss. This article is protected by copyright. All rights reserved.
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