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In developing an effective clinical tool against COVID-19, we need to consider why SARS-CoV-2 infections develops along remarkably different trajectories: from completely asymptomatic to a severe course of disease. In this paper we hypothesize that the progressive exhaustion and loss of lymphocytes associated with severe stages of COVID-19 results from an intracellular energy deficit in an organism which has already been depleted by preexisting chronic diseases, acute psychological stress and the aging process. A bioenergetics view of COVID-19 immunopathology opens a new biophysical opportunity to enhance impaired immune function via proposed pathways of photomagnetic catalysis of ATP synthesis, regenerative photobiomodulation and the ultrasonic acceleration of cell restructuring. Moreover, we suggest that a coherent application of multiple biophysical radiances (coMra) may synergistically enhance energy-matter-information kinetics of basal self-regeneration of cells and thus improve immune function and accelerate recovery.
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10.1016/j.jphotobiol.2020.112083
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document_parses/pdf_json/4cdc196c39139422f89a788d03b5b1d33fb34552.json
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document_parses/pmc_json/PMC7659653.xml.json
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The bioenergetics of COVID-19 immunopathology and the therapeutic potential of biophysical radiances
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