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INTRODUCTION: Involvement of the large vessels is rarely reported and poorly understood in cases of Corona virus disease-19 (COVID-19). The aim of this study is to present a series of cases with large vessel thrombosis (LVT). METHODS: This is a multicenter prospective case series study. The participants were consecutive in order. All the patients were diagnosed as cases of COVID-19 with documented LVT were included in the study. Large vessels were defined as any vessel equal or larger than popliteal artery. The mean duration of follow up was 4 months. RESULTS: The study included 22 cases, 19 (86.4%) cases were male, 3 (13.6%) patients were females. The age ranged from 23 to 76 with a mean of 48.4 years. Four (18.2%) cases had pulmonary embolism confirmed by IV contrast enhanced chest CT scan. All of the cases showed pulmonary parenchymal ground glass opacities (GGO) and high D-Dimers (ranging from 1267 to 6038 ng/ml with a mean of 3601 ng/ml). CONCLUSION: COVID-19 is a hidden risk factor of LVT that may endanger the patient\'s life and lead to major amputation. Despite therapeutic anticoagulants still all COVID-19 patient are at risk for LVT, a high index of suspicion should be created and with minimal symptoms surgical consultation should be obtained.
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10.1016/j.amsu.2020.11.030
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document_parses/pdf_json/0e9ca3ea30e8289e7721e903c145c164877c666c.json
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document_parses/pmc_json/PMC7658560.xml.json
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Large vessel thrombosis in patient with COVID-19, a case series
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