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How respiratory physiology and airflow therein proceed to impact SARS-CoV-2 transmission, leading to the initial infection, is an open question. An answer can help determine the susceptibility of an individual on exposure to a COVID-2019 carrier and can also quantify the still-unknown infectious dose for the disease. Combining computational fluid mechanics-based tracking of respiratory transport in anatomic domains with sputum assessment data from hospitalized patients and earlier measurements of ejecta size distribution during regular speech - this study shows that targeted deposition at the initial nasopharyngeal infection sites peaks over the droplet size range of 2.5 - 19 , and reveals that the number of virions that can establish the infection is at most of O(100).
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?:doi
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10.1101/2020.07.27.20162362
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document_parses/pdf_json/e9025aeb9a855b10f7be0e796fabdc3d31a9557b.json
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?:title
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Close-range exposure to a COVID-19 carrier: transmission trends in the respiratory tract and estimation of infectious dose
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