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BACKGROUND The COVID-19 outbreak has affected the lives of millions of people by causing a dramatic impact on several healthcare systems and the global economy. This devastating pandemic has brought communities across the globe to work on this issue in an unprecedented manner. OBJECTIVE This case study describes the steps and methods employed in the conduction of a remote online health hackathon centered on challenges the COVID-19 pandemic poses. It aims to deliver a clear implementation road map for other organizations to follow. METHODS This 4-day hackathon was conducted in April 2020, based on 6 COVID-19-related challenges defined by frontline clinicians and researchers from various disciplines. An online survey was structured to assess: (i) individual experience satisfaction, (ii) level of interprofessional skill exchange, (iii) maturity of the projects realized, and (iv) overall quality of the event. At the end of the event, participants were invited to participate in an online survey with 17 (+5 optional) items, including multiple-choice and open-ended questions which assessed their experience regarding the remote character of the event and their individual project, interprofessional skill exchange, and their confidence in working on a digital health project before and after the hackathon. Complementary, mentors, who guided the participants through the event also provided feedback to the organizers through an online survey. RESULTS A total of 48 participants and 52 mentors based in 8 different countries participated and developed 14 projects. A total of 75 mentorship video sessions were held. Participants reported increased confidence in starting a digital health venture or a research project after successfully participating in the hackathon, and are likely to continue working on their projects. Of the participants that provided feedback, 60% (n=18) would not have started their project without this particular hackathon, and indicated that the hackathon encouraged and enabled them to progress faster, eg by building interdisciplinary teams, gaining new insights and feedback provided by the mentors, and creating a functional prototype. CONCLUSIONS This study provides insights into how online hackathons can contribute to solving the challenges and effects of a pandemic in several regions of the world. The online format fosters team diversity, increases cross-regional collaboration, and can be executed much faster and at lower costs compared to in-person events. Results on preparation, organization, and evaluation of this online hackathon are useful to other institutions and initiatives which are willing to introduce similar event formats in the fight against COVID-19. CLINICALTRIAL
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