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?:abstract
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On the 9th March 2020, the first patient with COVID-19 was admitted to ICU in the Royal Gwent Hospital (RGH), Newport, Wales We prospectively recorded the rate of ICU admissions of 52 patients with COVID-19 over 60 days, focusing on the epidemiology of ethnicity and deprivation because these factors have emerged as significant risk factors Patients were 65% (34 of 52) male and had a median (IQR) age of 55 (48-62) years Prevalent comorbidities included obesity (52%);diabetes (33%), and asthma (23%) COVID-19 hospital and ICU inpatient numbers peaked on days 23 and 39, respectively-a lag of 16 days The ICU mortality rate was 33% (17 of 52) People of black, Asian, and minority ethnic descent (BAME group) represented 35% of ICU COVID-19 admissions (18 of 52) and 35% of deaths (6 of 17) Amongst the BAME group, 72% (13 of 18) of patients were found to reside in geographical areas representing the 20% most deprived in Wales, vs 27% of patients in the Caucasian group (9 of 33) Less than 5% of the population within the area covered by RGH are of BAME descent, yet this group had a disproportionately high ICU admission and mortality rate from COVID-19 The interplay between ethnicity and deprivation, which is complex, may be a factor in our findings This in turn could be related to an increased prevalence of co-morbidities;higher community exposure;larger proportion of lower band key worker roles;or genetic polymorphisms
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