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In patients coinfected with SARS-CoV-2 and HBV, liver injury was common. However, the interactions between SARS-CoV-2 and HBV coinfection remained unknown. Sixty-seven COVID-19 patients from the previous cohort were enrolled and classified into 2 groups (7 with HBsAg+ and 60 with HBsAg-). The association of HBV- and SARS-CoV-2-related markers were analyzed. During the acute course of SARS-CoV-2 infection, markers of HBV replication did not extensively fluctuate during SARS-CoV-2 infection. Coinfection with HBV did not extend the viral shedding cycle or incubation periods of SARS-CoV-2. Effects of SARS-CoV-2 on the dynamics of chronic HBV infection seemed not apparent. SARS-CoV-2 infection would not be the source of HBV reactivation in these individuals.
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10.1016/j.virol.2020.11.012
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document_parses/pdf_json/1c1fce89e12e0ae13671e86fc36d3452cad84c40.json
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document_parses/pmc_json/PMC7698656.xml.json
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Effect of SARS-CoV-2 coinfection was not apparent on the dynamics of chronic hepatitis B infection
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