PropertyValue
?:abstract
  • The complexity of the human immune system is exacerbated by age-related changes to immune cell functionality. Many of these age-related effects remain undescribed or driven by mechanisms that are poorly understood. γδ T cells, while considered an adaptive subset based on immunological ontogeny, retain both innate-like and adaptive-like characteristics. This T cell population is small but mighty, and has been implicated in both homeostatic and disease-induced immunity within tissues and throughout the periphery. In this review, we outline what is known about the effect of age on human peripheral γδ T cells, and call attention to areas of the field where further research is needed.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.3390/ijms21238903
?:journal
  • Int_J_Mol_Sci
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/106774254c77219100b76dcdb8b0c360362d3e01.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7727649.xml.json
?:pmcid
?:pmid
?:pmid
  • 33255339.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • A Cell for the Ages: Human γδ T Cells across the Lifespan
?:type
?:year
  • 2020-11-24

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