?:abstract
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Objectives: One-fifth of Covid-19 patients suffer a severe course of Covid-19 infection;however, the specific causes remain unclear Mast cells (MCs) are activated by SARS-CoV-2 Although only recently recognized, MC activation syndrome (MCAS), usually due to acquired MC clonality, is a chronic multisystem disorder with inflammatory and allergic themes, and an estimated prevalence of 17% This paper describes a novel conjecture explaining how MCAS might cause a propensity for severe acute Covid-19 infection and chronic post-Covid-19 illnesses
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