PropertyValue
?:abstract
  • Since the onset of the COVID-19 pandemic in the fall of 2019 over 4 million people have been infected and over 280,000 have died (1). Information about the SARS-CoV2 virus is evolving rapidly. At this time there are no interventions proven to be effective for cases infected with SARS-CoV2. Current knowledge about the clinical and laboratory manifestations of COVID-19 infection is reviewed and combined with knowledge about the immunopathogenic mechanisms of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV1) and Middle East Respiratory Syndrome (MERS) to formulate theories and suggest possible therapeutic interventions. SARS-CoV2 immunopathogenic mechanisms vary from immunosuppression that initially enables viral escape to a hyperinflammatory immune response. Ultimately therapeutic intervention will be phase dependent.
is ?:annotates of
?:creator
?:doi
  • 10.3389/fimmu.2020.564925
?:doi
?:journal
  • Front_Immunol
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/51208944ce6589eae19bdbcce3aeaa8eb4d2dfd4.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7533543.xml.json
?:pmcid
?:pmid
?:pmid
  • 33072103.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Immunopathogenesis of COVID-19: Summary and Possible Interventions
?:type
?:year
  • 2020-09-17

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