ct1x590

Property	Value
?:abstract	BACKGROUND: Thrombosis and pulmonary embolism appear to be major causes of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients. However, few studies have focused on the incidence of venous thromboembolism (VTE) after hospitalization for COVID-19. METHODS: In this multi-center study, we followed 1529 COVID-19 patients for at least 45 days after hospital discharge, who underwent routine telephone follow-up. In case of signs or symptoms of pulmonary embolism (PE) or deep vein thrombosis (DVT), they were invited for an in-hospital visit with a pulmonologist. The primary outcome was symptomatic VTE within 45 days of hospital discharge. RESULTS: Of 1529 COVID-19 patients discharged from hospital, a total of 228 (14.9%) reported potential signs or symptoms of PE or DVT and were seen for an in-hospital visit. Of these, 13 and 12 received Doppler ultrasounds or pulmonary CT angiography, respectively, of whom only one patient was diagnosed with symptomatic PE. Of 51 (3.3%) patients who died after discharge, two deaths were attributed to VTE corresponding to a 45-day cumulative rate of symptomatic VTE of 0.2% (95%CI 0.1%–0.6%; n = 3). There was no evidence of acute respiratory distress syndrome (ARDS) in these patients. Other deaths after hospital discharge included myocardial infarction (n = 13), heart failure (n = 9), and stroke (n = 9). CONCLUSIONS: We did not observe a high rate of symptomatic VTE in COVID-19 patients after hospital discharge. Routine extended thromboprophylaxis after hospitalization for COVID-19 may not have a net clinical benefit. Randomized trials may be warranted.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/1ct1x590_hasAnnotation_C0034065> <https://research.tib.eu/covid-19/entity/1ct1x590_hasAnnotation_C0040053> <https://research.tib.eu/covid-19/entity/1ct1x590_hasAnnotation_C0630906> <https://research.tib.eu/covid-19/entity/1ct1x590_hasAnnotation_C1457887>
?:creator	<https://research.tib.eu/covid-19/entity/Rashidi%2C_Farid%3B_Barco%2C_Stefano%3B_Kamangar%2C_Farin%3B_Heresi%2C_Gustavo_A.%3B_Emadi%2C_Ashkan%3B_Kaymaz%2C_Cihangir%3B_Jansa%2C_Pavel%3B_Reis%2C_Abilio%3B_Rashidi%2C_Arash%3B_Taghizadieh%2C_Ali%3B_Rezaeifar%2C_Parisa%3B_Moghimi%2C_Minoosh%3B_Ghodrati%2C_Samad%3B_Mozafari%2C_Abolfazl%3B_Foumani%2C_Ali_Alavi%3B_Tahamtan%2C_Ouria%3B_Rafiee%2C_Effat%3B_Abbaspour%2C_Zahra%3B_Khodadadi%2C_Kasra%3B_Alamdari%2C_Golsa%3B_Boodaghi%2C_Yasman%3B_Rezaei%2C_Maryam%3B_Muhammadi%2C_Muhammad_Javad%3B_Abbasi%2C_Meysam%3B_Movaseghi%2C_Fatemeh%3B_Koohi%2C_Ata%3B_Shakourzad%2C_Leila%3B_Ebrahimi%2C_Fatemeh%3B_Radvar%2C_Sarvin%3B_Amoozadeh%2C_Maryam%3B_Fereidooni%2C_Fatemeh%3B_Naseari%2C_Hanieh%3B_Movalled%2C_Kobra%3B_Ghorbani%2C_Ozra%3B_Ansarin%2C_Khalil>
?:doi	<https://research.tib.eu/covid-19/entity/10.1016/j.thromres.2020.12.001>
?:doi	10.1016/j.thromres.2020.12.001
?:journal	Thromb_Res
?:license	no-cc
?:pdf_json_files	document_parses/pdf_json/6105b25812f3e114468dfd7534d45f8bdfc046d9.json
?:pmc_json_files	document_parses/pmc_json/PMC7836837.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7836837>
?:pmid	<https://research.tib.eu/covid-19/entity/33338976.0>
?:pmid	33338976.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:sha_id	<https://research.tib.eu/covid-19/entity/6105b25812f3e114468dfd7534d45f8bdfc046d9>
?:source	Elsevier; Medline; PMC
?:title	Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: Prospective results from a multi-center study
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-12-11

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Value

?:abstract

BACKGROUND: Thrombosis and pulmonary embolism appear to be major causes of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients. However, few studies have focused on the incidence of venous thromboembolism (VTE) after hospitalization for COVID-19. METHODS: In this multi-center study, we followed 1529 COVID-19 patients for at least 45 days after hospital discharge, who underwent routine telephone follow-up. In case of signs or symptoms of pulmonary embolism (PE) or deep vein thrombosis (DVT), they were invited for an in-hospital visit with a pulmonologist. The primary outcome was symptomatic VTE within 45 days of hospital discharge. RESULTS: Of 1529 COVID-19 patients discharged from hospital, a total of 228 (14.9%) reported potential signs or symptoms of PE or DVT and were seen for an in-hospital visit. Of these, 13 and 12 received Doppler ultrasounds or pulmonary CT angiography, respectively, of whom only one patient was diagnosed with symptomatic PE. Of 51 (3.3%) patients who died after discharge, two deaths were attributed to VTE corresponding to a 45-day cumulative rate of symptomatic VTE of 0.2% (95%CI 0.1%–0.6%; n = 3). There was no evidence of acute respiratory distress syndrome (ARDS) in these patients. Other deaths after hospital discharge included myocardial infarction (n = 13), heart failure (n = 9), and stroke (n = 9). CONCLUSIONS: We did not observe a high rate of symptomatic VTE in COVID-19 patients after hospital discharge. Routine extended thromboprophylaxis after hospitalization for COVID-19 may not have a net clinical benefit. Randomized trials may be warranted.

is ?:annotates of