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?:abstract
  • One of the small-molecule drugs that’s getting attention as a possible coronavirus treatment is Ivermectin, which is an interesting story from a couple of different directions I’ve been getting some inquiries about it, so I thought it was time to have a look Ivermectin and COVID-19: So what is this compound doing in the news with the coronavirus? Its ion-channel mechanism of action against parasites has no application to viruses But it has been shown several times to have activity in cell assays against Dengue infection and to reduce viral loads in the mosquito vectors (see this paper and references therein), although the reasons for this are still unknown There have been some human studies for efficacy, but all I can find out is that a preliminary read showed no reduction of viral load in the infected patients, and there seems to have been no update But since denguevirus is also a single-strand positive-sense RNA virus, Ivermectin has come up as a possible coronavirus drug, mechanism or not
is ?:annotates of
?:creator
?:journal
  • Science
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • What’s Up With Ivermectin?
?:type
?:who_covidence_id
  • #232771
?:year
  • 2020

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