PropertyValue
?:abstract
  • False-negative SARS-CoV-2 test results can negatively impact the clinical and public health response to COVID-19. We used droplet digital PCR (ddPCR) to demonstrate that human DNA levels, a stable molecular marker of sampling quality, were significantly lower in samples from 40 confirmed or suspected COVID-19 cases that yielded negative diagnostic test results (i.e. suspected false-negative test results) compared to a representative pool of 87 specimens submitted for COVID-19 testing. Our results support suboptimal biological sampling as a contributor to false-negative COVID-19 test results and underscore the importance of proper training and technique in the collection of nasopharyngeal specimens.
?:creator
?:doi
?:doi
  • 10.1093/infdis/jiaa370
?:journal
  • J_Infect_Dis
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/284aed341739978fb3e8ca559dc5501f2c238336.json
?:pmcid
?:pmid
?:pmid
  • 32594170.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Suboptimal biological sampling as a probable cause of false-negative COVID-19 diagnostic test results
?:type
?:year
  • 2020-06-28

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