tzagl7j | Knowledge4COVID-19

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?:abstract	Angiotensin converting enzyme-2 (ACE-2) is the cell-surface receptor enabling viral uptake of corona virus 2019 (SARS-CoV-2), thus ACE-2 is a first step towards COVID-19 disease. ACE-2 is a metalloenzyme located primarily on the apical surface, and serves as the entry point also for other coronaviruses, including HCoV-NL63 and SARS-CoV. Throughout evolution, ACE-2 precedes renin, suggesting that ACE-2\'s role changed over time.1.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/1tzagl7j_hasAnnotation_C5203676>
?:creator	<https://research.tib.eu/covid-19/entity/Ye%2C_Qing%3B_Lai%2C_En_Yin%3B_Luft%2C_Friedrich_C%3B_Persson%2C_Pontus_B%3B_Mao%2C_Jianhua>
?:doi	<https://research.tib.eu/covid-19/entity/10.1111/apha.13608>
?:doi	10.1111/apha.13608
?:journal	Acta_physiologica
?:license	unk
?:pmid	<https://research.tib.eu/covid-19/entity/33350096>
?:pmid	33350096
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:source	Medline
?:title	SARS-CoV-2 effects on the renin-angiotensin-aldosterone system, therapeutic implications.
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-12-22

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