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?:abstract
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Background: Information about critically ill patients with coronavirus disease 2019 (COVID-19) in China but outside of Wuhan is scarce We aimed to describe the clinical features, treatment, and outcomes of patients with COVID-19 admitted to the intensive care unit (ICU) in Guangdong Province Methods: In this multicenter, retrospective, observational study, we enrolled consecutive patients with COVID-19 who were admitted to seven ICUs in Guangdong Province Demographic data, symptoms, laboratory findings, comorbidities, treatment, and outcomes were collected Data were compared between patients with and without intubation Results: A total of 45 COVID-19 patients required ICU admission in the study hospitals [mean age 56 7 ± 15 4 years, 29 males (64 4%)] The most common symptoms at onset were fever and cough Most patients presented with lymphopenia and elevated lactate dehydrogenase Treatment with antiviral drugs was initiated in all patients Thirty-six patients (80%) developed acute respiratory distress syndrome at ICU admission, and 15 (33 3%) septic shock Twenty patients (44 4%) were intubated, and 10 (22 2%) received extracorporeal membrane oxygenation The 60-day mortality was 4 4% (2 of 45) Conclusion: COVID-19 patients admitted to ICU were characterized by fever, lymphopenia, acute respiratory failure, and multiple organ dysfunction The mortality of ICU patients in Guangdong Province was relatively low with a small sample size © Copyright © 2020 Xu, Xu, Liu, Cai, Zheng, Huang, Zhou, Huang, Ling, Deng, Li, Chen, Liu, Lin, Zhou, He, Zhong, Liu and Li
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