izb8mw7 | Knowledge4COVID-19

Property	Value
?:abstract	On human lung parenchymal explants, chloroquine concentration clinically achievable in the lung (100 µM) inhibited the lipopolysaccharide-induced release of TNF-É (by 76%), IL-6 (by 68%), CCL2 (by 72%), and CCL3 (by 67%). Besides its antiviral activity, chloroquine might also mitigate the cytokine storm associated with severe pneumonia caused by coronaviruses.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/2izb8mw7_hasAnnotation_C0023810> <https://research.tib.eu/covid-19/entity/2izb8mw7_hasAnnotation_C0206419>
?:creator	<https://research.tib.eu/covid-19/entity/Grassin-Delyle%2C_Stanislas%3B_Salvator%2C_H%C3%A9l%C3%A8ne%3B_Brollo%2C_Marion%3B_Catherinot%2C_Emilie%3B_Sage%2C_Edouard%3B_Couderc%2C_Louis-Jean%3B_Naline%2C_Emmanuel%3B_Devillier%2C_Philippe>
?:journal	Clin_Infect_Dis
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/2izb8mw7_HAS_C0008269_TREATS_C0919747> <https://research.tib.eu/covid-19/entity/2izb8mw7_HAS_C0032285_COEXISTS_WITH_C0919747> <https://research.tib.eu/covid-19/entity/2izb8mw7_HAS_C0206419_CAUSES_C0032285>
?:source	WHO
?:title	Chloroquine Inhibits the Release of Inflammatory Cytokines by Human Lung Explants
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#209687
?:year	2020

Metadata

Anon_0

<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>

<http://purl.org/net/provenance/ns#DataItem>

<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>

<http://www.w3.org/2004/03/trix/rdfg-1/Graph>

<http://xmlns.com/foaf/0.1/primaryTopic>

<https://research.tib.eu/covid-19/entity/2izb8mw7>

<http://xmlns.com/foaf/0.1/topic>

Anon_0

<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes>

<https://research.tib.eu/covid-19/data/entity/2izb8mw7>

<http://purl.org/net/provenance/ns#createdBy>

Anon_1 (more)

expand all