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A critical lack of personal protective equipment has occurred during the COVID-19 pandemic Polylactic acid (PLA), a polyester made from renewable natural resources, can be exploited for 3D printing of protective face masks using the Fused Deposition Modelling technique Since the possible high porosity of this material raised questions regarding its suitability for protection against viruses, we have investigated its microstructure using scanning electron microscopy and aerosol generator and photometer certified as the test system according to the standards EN 143 and EN 149 Moreover, the efficiency of decontaminating PLA surfaces by conventional chemical disinfectants including 96% ethanol, 70% isopropanol, and a commercial disinfectant containing 0 85% sodium hypochlorite has been determined We confirmed that the structure of PLA protective masks is compact and can be considered a sufficient barrier protection against particles of a size corresponding to microorganisms including viruses Complete decontamination of PLA surfaces from externally applied Staphylococcus epidermidis, Escherichia coli, Candida albicans and SARS-CoV-2 was achieved using all disinfectants tested, and human adenovirus was completely inactivated by sodium hypochlorite-containing disinfectant Natural contamination of PLA masks worn by test persons was decontaminated easily and efficiently by ethanol No disinfectant caused major changes to the PLA surface properties, and the pore size did not change despite severe mechanical damage of the surface Therefore, PLA may be regarded as a suitable material for 3D printing of protective masks during the current or future pandemic crises
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