PropertyValue
?:abstract
  • [Image: see text] Mass spectrometry (MS) can deliver valuable diagnostic data that complement genomic information and allow us to increase our current knowledge of the COVID-19 disease caused by the SARS-CoV-2 virus. We developed a simple, MS-based method to specifically detect SARS-CoV-2 proteins from gargle solution samples of COVID-19 patients. The protocol consists of an acetone precipitation and tryptic digestion of proteins contained within the gargle solution, followed by a targeted MS analysis. Our methodology identifies unique peptides originating from SARS-CoV-2 nucleoprotein. Building on these promising initial results, faster MS protocols can now be developed as routine diagnostic tools for COVID-19 patients. Data are available via ProteomeXchange with identifier PXD019423.
?:creator
?:doi
  • 10.1021/acs.jproteome.0c00280
?:doi
?:journal
  • J_Proteome_Res
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/3e4e3262093a3cb8aa960caf54b193dee03f6a9f.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7315851.xml.json
?:pmcid
?:pmid
?:pmid
  • 32568543.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients
?:type
?:year
  • 2020-06-22

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/31trqhi1>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/31trqhi1>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all