PropertyValue
?:abstract
  • Virus shedding in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur before onset of symptoms; less is known about symptom progression or infectiousness associated with initiation of viral shedding. We investigated household transmission in 5 households with daily specimen collection for 5 consecutive days starting a median of 4 days after symptom onset in index patients. Seven contacts across 2 households implementing no precautionary measures were infected. Of these 7, 2 tested positive for SARS-CoV-2 by reverse transcription PCR on day 3 of 5. Both had mild, nonspecific symptoms for 1–3 days preceding the first positive test. SARS-CoV-2 was cultured from the fourth-day specimen in 1 patient and from the fourth- and fifth-day specimens in the other. We also describe infection control measures taken in the households that had no transmission. Persons exposed to SARS-CoV-2 should self-isolate, including from household contacts, wear a mask, practice hand hygiene, and seek testing promptly.
is ?:annotates of
?:creator
?:doi
  • 10.3201/eid2702.203517
?:doi
?:journal
  • Emerg_Infect_Dis
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/d51be7639937c4be3225860a51ad9d8396e9a358.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7853554.xml.json
?:pmcid
?:pmid
?:pmid
  • 33275874.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Characteristics and Timing of Initial Virus Shedding in Severe Acute Respiratory Syndrome Coronavirus 2, Utah, USA
?:type
?:year
  • 2021-02-15

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