PropertyValue
?:abstract
  • OBJECTIVE: To estimate the feasibility, acceptability, and safety of outpatient penicillin allergy testing among pregnant women. METHODS: We conducted a prospective cohort study at a large academic hospital from March 2019 to March 2020. We recruited pregnant women with a self-reported penicillin allergy who underwent allergy testing between 14 0/7 and 36 6/7 weeks of gestation. RESULTS: Of 127 eligible women pregnant women, 74 (58%, 95% CI 4–67%) accepted allergy testing. Fifty completed or intended to complete allergy testing, yielding a feasibility rate of 68% (95% CI 56–78%). Among the 46 women actually tested (who ranged in age from 18 to 42), 93% (95% CI 68–100%) had a negative test result. A systemic reaction (symptoms consistent with anaphylaxis) occurred in only 2 women (4%, 95% CI 0.5–15%) despite 20 (43%) reporting a severe allergy. No woman suffered an adverse event as a result of allergy testing. In multivariate analysis adjusting for age and parity, women with public insurance had decreased odds of undergoing penicillin allergy testing (adjusted odds ratio 0.24, 95% CI 0.08–0.69). CONCLUSION: Outpatient penicillin allergy testing is acceptable and feasible in pregnancy.
is ?:annotates of
?:creator
?:doi
  • 10.1097/aog.0000000000004213
?:doi
?:journal
  • Obstet_Gynecol
?:license
  • cc-by-nc-nd
?:pdf_json_files
  • document_parses/pdf_json/a0fd5baca428db42cc2477a94a1c1b46ec5283c9.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7737873.xml.json
?:pmcid
?:pmid
?:pmid
  • 33278285.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Outpatient Penicillin Allergy Testing in Pregnant Women Who Report an Allergy
?:type
?:year
  • 2020-12-01

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