Property | Value |
?:abstract
|
-
Identification of potential drug-target interaction for approved drugs serves as the basis of repurposing drugs Studies have shown polypharmacology as common phenomenon In-silico approaches helin screening large compound libraries at once which could take years in a laboratory We screened a library of 1050 FDA-approved drugs against spike glycoprotein of SARS-CoV2 in-silico Anti-cancer drugs have shown good binding affinity which is much better than hydroxychloroquine and arbidol We have also introduced a hypothesis named “Bump†hypothesis which and be developed further in field of computational biology
|
is
?:annotates
of
|
|
?:creator
|
|
?:license
|
|
?:publication_isRelatedTo_Disease
|
|
?:source
|
|
?:title
|
-
In-Silico FDA-Approved Drug Repurposing to Find the Possible Treatment of Coronavirus Disease-19 (COVID-19)
|
?:type
|
|
?:who_covidence_id
|
|
?:year
|
|