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SUMMARY: While over 200 000 genomic sequences are currently available through dedicated repositories, ad hoc methods for the functional annotation of SARS-CoV-2 genomes do not harness all currently available resources for the annotation of functionally relevant genomic sites. Here, we present CorGAT, a novel tool for the functional annotation of SARS-CoV-2 genomic variants. By comparisons with other state of the art methods we demonstrate that, by providing a more comprehensive and rich annotation, our method can facilitate the identification of evolutionary patterns in the genome of SARS-CoV-2. AVAILABILITYAND IMPLEMENTATION: Galaxy : http://corgat.cloud.ba.infn.it/galaxy; software: https://github.com/matteo14c/CorGAT/tree/Revision_V1; docker: https://hub.docker.com/r/laniakeacloud/galaxy_corgat. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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10.1093/bioinformatics/btaa1047
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document_parses/pdf_json/98061c420df170b08add76ab5a1230d09786d451.json
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document_parses/pmc_json/PMC7799324.xml.json
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CorGAT: a tool for the functional annotation of SARS-CoV-2 genomes
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