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OBJECTIVE: We aimed to explore the prevalence of smoking rates and comorbidities and evaluate the relationship between them and disease severity and mortality in inpatients with COVID-19. METHODS: COVID-19 patients were divided into the following groups: clinic group, intensive care unit (ICU) group, survivors, and non-survivors. Non-COVID-19 patients were included as a control group. The groups were compared. RESULTS: There was no difference between patients with and without COVID-19 in terms of smoking, asthma, diabetes, dementia, coronary artery disease (CAD), hypertension, chronic renal failure and arrhythmia (p>0.05). Older age (Odds ratio (OR), 1.061; 95% confidence interval (CI): 1.041-1.082; p< 0.0001), chronic obstructive pulmonary disease (COPD) (OR, 2.775; 95% CI: 1.128-6.829; p=0.026) and CAD (OR, 2.696; 95% CI: 1.216-5.974; p=0.015) were significantly associated with ICU admission. Current smoking (OR, 5.101; 95% CI: 2.382-10.927; p<0.0001) and former smoking (OR, 3.789; 95% CI: 1.845-7.780; p<0.0001) were risk factors for ICU admission. Older age (OR; 1.082; 95% CI: 1.056-1.109; p<0.0001), COPD (OR, 3.213; 95% CI: 1.224-8.431; p=0.018), CAD (OR, 6.252; 95% CI: 2.171-18.004; p=0.001) and congestive heart failure (CHF) (OR, 5.917; 95% CI 1.069-32.258; p=0.042), were significantly associated with mortality. Current smoking (OR, 13.014; 95% CI: 5.058-33.480; p<0.0001) and former smoking (OR, 6.507; 95% CI 2.731-15.501; p<0.0001) were also risk factors for mortality. CONCLUSION: Smoking, older age, COPD, and CAD were risk factors for ICU admission and mortality in patients with COVID-19. CHF was not a risk factor for ICU admission; however, it was a risk factor for mortality.
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SUMMARY OBJECTIVE: We aimed to explore the prevalence of smoking rates and comorbidities and evaluate the relationship between them and disease severity and mortality in inpatients with COVID-19 METHODS: COVID-19 patients were divided into the following groups: clinic group, intensive care unit (ICU) group, survivors, and non-survivors Non-COVID-19 patients were included as a control group The groups were compared RESULTS: There was no difference between patients with and without COVID-19 in terms of smoking, asthma, diabetes, dementia, coronary artery disease (CAD), hypertension, chronic renal failure and arrhythmia (p>0 05) Older age (Odds ratio (OR), 1 061;95% confidence interval (CI): 1 041-1 082;p<0 0001), chronic obstructive pulmonary disease (COPD) (OR, 2 775;95% CI: 1 128-6 829;p=0 026) and CAD (OR, 2 696;95% CI: 1 216-5 974;p=0 015) were significantly associated with ICU admission Current smoking (OR, 5 101;95% CI: 2 382-10 927;p<0 0001) and former smoking (OR, 3 789;95% CI: 1 845-7 780;p<0 0001) were risk factors for ICU admission Older age (OR;1 082;95% CI: 1 056-1 109;p<0 0001), COPD (OR, 3 213;95% CI: 1 224-8 431;p=0 018), CAD (OR, 6 252;95% CI: 2 171-18 004;p=0 001) and congestive heart failure (CHF) (OR, 5 917;95% CI 1 069-32 258;p=0 042), were significantly associated with mortality Current smoking (OR, 13 014;95% CI: 5 058-33 480;p<0 0001) and former smoking (OR, 6 507;95% CI 2 731-15 501;p<0 0001) were also risk factors for mortality CONCLUSION: Smoking, older age, COPD, and CAD were risk factors for ICU admission and mortality in patients with COVID-19 CHF was not a risk factor for ICU admission;however, it was a risk factor for mortality RESUMO OBJETIVO: Buscamos explorar as taxas de prevalência de tabagismo e de comorbidades e avaliar a relação entre elas e a severidade e mortalidade da doença em pacientes hospitalizados com COVID-19 MÉTODOS: Pacientes com COVID-19 foram divididos nos seguintes grupos: grupo clínico, grupo da unidade de terapia intensiva (UTI), grupo de sobreviventes e não-sobreviventes Pacientes sem COVID-19 foram incluídos em um grupo de controle Os grupos foram comparados RESULTADOS: Não houve diferença entre os pacientes com e sem COVID-19 em termos de tabagismo, asma, diabetes, demência, doença arterial coronariana (DAC), hipertensão arterial, insuficiência renal crônica e arritmia (p>0,05) Idade mais avançada (odds ratio (OR), 1,061;95% de intervalo de confiança (IC): 1,041-1,082;p<0,0001), doença pulmonar obstrutiva crônica (DPOC) (OR, 2,775;95% IC: 1,128-6,829;p=0,026) e DAC (OR, 2,696;95% IC: 1,216-5,974;p=0,015) estavam significativamente associados com a admissão na UTI O tabagismo atual (OR, 5,101;95% IC: 2,382-10,927;p <0,0001) e tabagismo prévio (OR, 3,789;95% IC: 1,845-7,780;p<0,0001) foram fatores de risco para admissão na UTI Idade mais avançada (OR;1,082;95% IC: 1,056-1,109;<0,0001), DPOC (OR, 3,213;95% IC: 1,224-8,431;p=0,018), DAC (OR, 6,252;95% IC: 2,171-18,004;p=0,001) e insuficiência cardíaca congestiva (ICC) (OR, 5,917;95% IC 1,069-32,258;p=0,042) estavam significativamente associados com mortalidade O tabagismo atual (OR, 13,014;95% IC: 5,058-33,480;p<0,0001) e o tabagismo prévio (OR, 6,507;95% IC 2,731-15,501;p<0,0001) também foram fatores de risco para mortalidade CONCLUSÃO: O tabagismo, a idade avançada, DPOC e DAC foram fatores de risco para admissão na UTI e mortalidade em pacientes com COVID-19 ICC não foi um fator de risco para admissão na UTI;no entanto, foi um fator de risco para mortalidade
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