PropertyValue
?:abstract
  • COVID-19 greatly disrupted the global supply chain of nasopharyngeal swabs, and thus new products have come to market with little data to support their use In this prospective study, 2 new 3D printed nasopharyngeal swab designs were evaluated against the standard, flocked nasopharyngeal swab for the diagnosis of COVID-19 Seventy adult patients (37 COVID-positive and 33 COVID-negative) underwent consecutive diagnostic reverse transcription polymerase chain reaction testing, with a flocked swab followed by one or two 3D printed swabs The \'Lattice Swab\' (manufacturer Resolution Medical) demonstrated 93 3% sensitivity (95% CI, 77 9%-99 2%) and 96 8% specificity (83 3%-99 9%), yielding kappa=0 90 (0 85-0 96) The \'Origin KXG\' (manufacturer Origin Laboratories) demonstrated 83 9% sensitivity (66 3%-94 6%) and 100% specificity (88 8%-100 0%), yielding kappa=0 84 (0 77-0 91) Both 3D printed nasopharyngeal swab results have high concordance with the control swab results The decision to use 3D printed nasopharyngeal swabs during the COVID-19 pandemic should be strongly considered by clinical and research laboratories
  • COVID-19 greatly disrupted the global supply chain of nasopharyngeal swabs, and thus new products have come to market with little data to support their use. In this prospective study, 2 new 3D printed nasopharyngeal swab designs were evaluated against the standard, flocked nasopharyngeal swab for the diagnosis of COVID-19. Seventy adult patients (37 COVID-positive and 33 COVID-negative) underwent consecutive diagnostic reverse transcription polymerase chain reaction testing, with a flocked swab followed by one or two 3D printed swabs. The \'Lattice Swab\' (manufacturer Resolution Medical) demonstrated 93.3% sensitivity (95% CI, 77.9%-99.2%) and 96.8% specificity (83.3%-99.9%), yielding κ = 0.90 (0.85-0.96). The \'Origin KXG\' (manufacturer Origin Laboratories) demonstrated 83.9% sensitivity (66.3%-94.6%) and 100% specificity (88.8%-100.0%), yielding κ = 0.84 (0.77-0.91). Both 3D printed nasopharyngeal swab results have high concordance with the control swab results. The decision to use 3D printed nasopharyngeal swabs during the COVID-19 pandemic should be strongly considered by clinical and research laboratories.
is ?:annotates of
?:creator
?:journal
  • Diagn_Microbiol_Infect_Dis
  • Diagnostic_Microbiology_&_Infectious_Disease
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Prospective clinical validation of 3D printed nasopharyngeal swabs for diagnosis of COVID-19
?:type
?:who_covidence_id
  • #1065002
  • #885248
?:year
  • 2020

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