cget7rp

Property	Value
?:abstract	Background: COVID-19 clinical presentation is usually non-specific and includes commonly encountered symptoms like fever, cough, nausea, and vomiting. It has been reported that COVID-19 patients can potentially transmit the disease to others before developing symptoms. Thus, extensive surveillance and screening of individuals at risk of the disease is required to limit SARS-COV-2 spread. The COVID-19 respiratory triage score has been used for patient screening. We aimed to determine its diagnostic performance characteristics, which have not been adequately studied before. Methodology: This is a retrospective observational study involving all patients screened for COVID-19 at a tertiary care facility. Patients were tested using nasopharyngeal swab for SARS-COV-2 PCR. The Saudi CDC COVID-19 respiratory triage score was measured for all subjects. The sensitivity, specificity, positive predictive value, and negative predicted value of COVID-19 respiratory triage score were measured with reference to SARS-COV-2 PCR test. Multivariate regression analysis was done to identify factors that can predict a positive SARS-COV-2 PCR test. Result: A total of 1,435 subjects were included. The COVID-19 respiratory triage score provided a marginal diagnostic performance with a receiver-operating characteristics (ROC) area under the curve value of 0.60 (95% CI: 0.57–0.64). A triage score of 5 provided the best cut-off value for the combined sensitivity and specificity. Clinical characteristics that independently predicted positive COVID-19 PCR test include male sex (adjusted OR: 1.47; p = 0.034), healthcare workers and their family members (adjusted OR: 1.99; 95%; p = 0.016), fever (adjusted OR: 2.98; p < 0.001), and moderate disease severity (adjusted OR: 5; p < 0.001). Conclusion: The current COVID-19 respiratory triage score has marginal diagnostic performance characteristics. Its performance can improve by including additional predictors to the respiratory symptoms in order to avoid missing COVID-19 patients with atypical presentation and to limit unnecessary SARS-COV-2 PCR testing.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0010200> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0015967> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0020517> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0027497> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0037090> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C0042963> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C1457887> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C3539125> <https://research.tib.eu/covid-19/entity/4cget7rp_hasAnnotation_C5203676>
?:creator	<https://research.tib.eu/covid-19/entity/Aldobyany%2C_Ahmad%3B_Touman%2C_Abdelfattah%3B_Ghaleb%2C_Nabil%3B_Alsaggaf%2C_Rajaa%3B_Murtaza%2C_Noureen%3B_Hamada%2C_Adel%3B_Alknawy%2C_Moataz%3B_Albanna%2C_Amr_S.%3B_Alqurashi%2C_Eid>
?:doi	<https://research.tib.eu/covid-19/entity/10.3389/fmed.2020.605689>
?:doi	10.3389/fmed.2020.605689
?:journal	Front_Med_(Lausanne)
?:license	cc-by
?:pdf_json_files	document_parses/pdf_json/ef6b2f182bcb07f6ecda1b2de74f4583742439a6.json
?:pmc_json_files	document_parses/pmc_json/PMC7750529.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7750529>
?:pmid	<https://research.tib.eu/covid-19/entity/33365322.0>
?:pmid	33365322.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
?:sha_id	<https://research.tib.eu/covid-19/entity/ef6b2f182bcb07f6ecda1b2de74f4583742439a6>
?:source	Medline; PMC
?:title	Correlation Between the COVID-19 Respiratory Triage Score and SARS-COV-2 PCR Test
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-12-07

Property

Value

?:abstract

Background: COVID-19 clinical presentation is usually non-specific and includes commonly encountered symptoms like fever, cough, nausea, and vomiting. It has been reported that COVID-19 patients can potentially transmit the disease to others before developing symptoms. Thus, extensive surveillance and screening of individuals at risk of the disease is required to limit SARS-COV-2 spread. The COVID-19 respiratory triage score has been used for patient screening. We aimed to determine its diagnostic performance characteristics, which have not been adequately studied before. Methodology: This is a retrospective observational study involving all patients screened for COVID-19 at a tertiary care facility. Patients were tested using nasopharyngeal swab for SARS-COV-2 PCR. The Saudi CDC COVID-19 respiratory triage score was measured for all subjects. The sensitivity, specificity, positive predictive value, and negative predicted value of COVID-19 respiratory triage score were measured with reference to SARS-COV-2 PCR test. Multivariate regression analysis was done to identify factors that can predict a positive SARS-COV-2 PCR test. Result: A total of 1,435 subjects were included. The COVID-19 respiratory triage score provided a marginal diagnostic performance with a receiver-operating characteristics (ROC) area under the curve value of 0.60 (95% CI: 0.57–0.64). A triage score of 5 provided the best cut-off value for the combined sensitivity and specificity. Clinical characteristics that independently predicted positive COVID-19 PCR test include male sex (adjusted OR: 1.47; p = 0.034), healthcare workers and their family members (adjusted OR: 1.99; 95%; p = 0.016), fever (adjusted OR: 2.98; p < 0.001), and moderate disease severity (adjusted OR: 5; p < 0.001). Conclusion: The current COVID-19 respiratory triage score has marginal diagnostic performance characteristics. Its performance can improve by including additional predictors to the respiratory symptoms in order to avoid missing COVID-19 patients with atypical presentation and to limit unnecessary SARS-COV-2 PCR testing.

is ?:annotates of