PropertyValue
?:abstract
  • Cell migration is an essential, energetically-demanding process in immunity. Immune cells navigate the body via chemokines and other immune mediators, which are altered under inflammatory conditions of injury or infection. Several factors determine the migratory abilities of different types of immune cells in diverse contexts, including the precise coordination of cytoskeletal remodeling, the expression of specific chemokine receptors and integrins, and environmental conditions. In this review, we present an overview of recent advances in our understanding of the relationship of each of these factors with cellular metabolism, with a focus on the spatial organization of glycolysis and mitochondria, reciprocal regulation of chemokine receptors, and the influence of environmental changes.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.1111/imm.13260
?:journal
  • Immunology
?:license
  • unk
?:pmid
?:pmid
  • 32920838
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • Medline
?:title
  • Implications of cellular metabolism for immune cell migration.
?:type
?:year
  • 2020-09-13

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