r16jcpd

Property	Value
?:abstract	OBJECTIVE: The aim of this study was to investigate the incidence, clinical presentation, cardiovascular (CV) complications, and mortality risk of myocardial injury on admission in critically ill intensive care unit (ICU) inpatients with COVID-19 DESIGN: A single-center, retrospective, observational study SETTING: A newly built ICU in Tongji hospital (Sino-French new city campus), Huazhong University of Science and Technology, Wuhan, China PARTICIPANTS: Seventy-seven critical COVID-19 patients INTERVENTIONS: Patients were divided into a myocardial injury group and nonmyocardial injury group according to the on-admission levels of high-sensitivity cardiac troponin I MEASUREMENTS AND MAIN RESULTS: Demographic data, clinical characteristics, laboratory tests, treatment, and clinical outcome were evaluated, stratified by the presence of myocardial injury on admission Compared with nonmyocardial injury patients, patients with myocardial injury were older (68 4 +/- 10 1 v 62 1 +/- 13 5 years;p=0 02), had higher prevalence of underlying CV disease (34 1% v 11 1%;p=0 02), and in-ICU CV complications (41 5% v 13 9%;p=0 008), higher Acute Physiology and Chronic Health Evaluation II scores (20 3 +/- 7 3 v 14 4 +/- 7 4;p=0 001), and Sequential Organ Failure Assessment scores (7, interquartile range (IQR) 5-10 v 5, IQR 3-6;p =75 years was another risk factor for mortality (HR, 2 882;95% CI 1 51-5 50;p=0 002) CONCLUSION: Critically ill patients with COVID-19 had a high risk of CV complications Myocardial injury on admission may be a common comorbidity and is associated with severity and a high risk of mortality in this population OBJECTIVE: The aim of this study was to investigate the incidence, clinical presentation, cardiovascular (CV) complications, and mortality risk of myocardial injury on admission in critically ill intensive care unit (ICU) inpatients with COVID-19. DESIGN: A single-center, retrospective, observational study. SETTING: A newly built ICU in Tongji hospital (Sino-French new city campus), Huazhong University of Science and Technology, Wuhan, China. PARTICIPANTS: Seventy-seven critical COVID-19 patients. INTERVENTIONS: Patients were divided into a myocardial injury group and nonmyocardial injury group according to the on-admission levels of high-sensitivity cardiac troponin I. MEASUREMENTS AND MAIN RESULTS: Demographic data, clinical characteristics, laboratory tests, treatment, and clinical outcome were evaluated, stratified by the presence of myocardial injury on admission. Compared with nonmyocardial injury patients, patients with myocardial injury were older (68.4 ± 10.1 v 62.1 ± 13.5 years; pâ¯=â¯0.02), had higher prevalence of underlying CV disease (34.1% v 11.1%; pâ¯=â¯0.02), and in-ICU CV complications (41.5% v 13.9%; pâ¯=â¯0.008), higher Acute Physiology and Chronic Health Evaluation II scores (20.3 ± 7.3 v 14.4 ± 7.4; pâ¯=â¯0.001), and Sequential Organ Failure Assessment scores (7, interquartile range (IQR) 5-10 v 5, IQR 3-6; p < 0.001). Myocardial injury on admission increased the risk of 28-day mortality (hazard ratio [HR], 2.200; 95% confidence interval [CI] 1.29 to 3.74; pâ¯=â¯0.004). Age ≥75 years was another risk factor for mortality (HR, 2.882; 95% CI 1.51-5.50; pâ¯=â¯0.002). CONCLUSION: Critically ill patients with COVID-19 had a high risk of CV complications. Myocardial injury on admission may be a common comorbidity and is associated with severity and a high risk of mortality in this population.
is ?:annotates of	<https://research.tib.eu/covid-19/entity/4r16jcpd_hasAnnotation_C0161816> <https://research.tib.eu/covid-19/entity/4r16jcpd_hasAnnotation_C0231218> <https://research.tib.eu/covid-19/entity/4r16jcpd_hasAnnotation_C0746730>
?:creator	<https://research.tib.eu/covid-19/entity/Qian%2C_H.%3B_Gao%2C_P.%3B_Tian%2C_R.%3B_Yang%2C_X.%3B_Guo%2C_F.%3B_Li%2C_T.%3B_Liu%2C_Z.%3B_Wang%2C_J.%3B_Zhou%2C_X.%3B_Qin%2C_Y.%3B_Chang%2C_L.%3B_Song%2C_Y.%3B_Yan%2C_X.%3B_Wu%2C_W.%3B_Zhang%2C_S.> <https://research.tib.eu/covid-19/entity/Qian%2C_Hao%3B_Gao%2C_Peng%3B_Tian%2C_Ran%3B_Yang%2C_Xufei%3B_Guo%2C_Fan%3B_Li%2C_Taisheng%3B_Liu%2C_Zhengyin%3B_Wang%2C_Jinglan%3B_Zhou%2C_Xiang%3B_Qin%2C_Yan%3B_Chang%2C_Long%3B_Song%2C_Yanjun%3B_Yan%2C_Xiaowei%3B_Wu%2C_Wei%3B_Zhang%2C_Shuyang>
?:journal	J._cardiothoracic_vasc._anest Journal_of_Cardiothoracic_&_Vascular_Anesthesia
?:license	unk
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/4r16jcpd_HAS_C0007222_COEXISTS_WITH_C0161816> <https://research.tib.eu/covid-19/entity/4r16jcpd_HAS_C2744535_PREDISPOSES_C0746730>
?:source	WHO
?:title	Myocardial Injury on Admission as a Risk in Critically Ill COVID-19 Patients: A Retrospective in-ICU Study
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:who_covidence_id	#1065991 #867607
?:year	2020 2021

Property

Value

?:abstract

OBJECTIVE: The aim of this study was to investigate the incidence, clinical presentation, cardiovascular (CV) complications, and mortality risk of myocardial injury on admission in critically ill intensive care unit (ICU) inpatients with COVID-19 DESIGN: A single-center, retrospective, observational study SETTING: A newly built ICU in Tongji hospital (Sino-French new city campus), Huazhong University of Science and Technology, Wuhan, China PARTICIPANTS: Seventy-seven critical COVID-19 patients INTERVENTIONS: Patients were divided into a myocardial injury group and nonmyocardial injury group according to the on-admission levels of high-sensitivity cardiac troponin I MEASUREMENTS AND MAIN RESULTS: Demographic data, clinical characteristics, laboratory tests, treatment, and clinical outcome were evaluated, stratified by the presence of myocardial injury on admission Compared with nonmyocardial injury patients, patients with myocardial injury were older (68 4 +/- 10 1 v 62 1 +/- 13 5 years;p=0 02), had higher prevalence of underlying CV disease (34 1% v 11 1%;p=0 02), and in-ICU CV complications (41 5% v 13 9%;p=0 008), higher Acute Physiology and Chronic Health Evaluation II scores (20 3 +/- 7 3 v 14 4 +/- 7 4;p=0 001), and Sequential Organ Failure Assessment scores (7, interquartile range (IQR) 5-10 v 5, IQR 3-6;p =75 years was another risk factor for mortality (HR, 2 882;95% CI 1 51-5 50;p=0 002) CONCLUSION: Critically ill patients with COVID-19 had a high risk of CV complications Myocardial injury on admission may be a common comorbidity and is associated with severity and a high risk of mortality in this population
OBJECTIVE: The aim of this study was to investigate the incidence, clinical presentation, cardiovascular (CV) complications, and mortality risk of myocardial injury on admission in critically ill intensive care unit (ICU) inpatients with COVID-19. DESIGN: A single-center, retrospective, observational study. SETTING: A newly built ICU in Tongji hospital (Sino-French new city campus), Huazhong University of Science and Technology, Wuhan, China. PARTICIPANTS: Seventy-seven critical COVID-19 patients. INTERVENTIONS: Patients were divided into a myocardial injury group and nonmyocardial injury group according to the on-admission levels of high-sensitivity cardiac troponin I. MEASUREMENTS AND MAIN RESULTS: Demographic data, clinical characteristics, laboratory tests, treatment, and clinical outcome were evaluated, stratified by the presence of myocardial injury on admission. Compared with nonmyocardial injury patients, patients with myocardial injury were older (68.4 ± 10.1 v 62.1 ± 13.5 years; pâ¯=â¯0.02), had higher prevalence of underlying CV disease (34.1% v 11.1%; pâ¯=â¯0.02), and in-ICU CV complications (41.5% v 13.9%; pâ¯=â¯0.008), higher Acute Physiology and Chronic Health Evaluation II scores (20.3 ± 7.3 v 14.4 ± 7.4; pâ¯=â¯0.001), and Sequential Organ Failure Assessment scores (7, interquartile range (IQR) 5-10 v 5, IQR 3-6; p < 0.001). Myocardial injury on admission increased the risk of 28-day mortality (hazard ratio [HR], 2.200; 95% confidence interval [CI] 1.29 to 3.74; pâ¯=â¯0.004). Age ≥75 years was another risk factor for mortality (HR, 2.882; 95% CI 1.51-5.50; pâ¯=â¯0.002). CONCLUSION: Critically ill patients with COVID-19 had a high risk of CV complications. Myocardial injury on admission may be a common comorbidity and is associated with severity and a high risk of mortality in this population.

is ?:annotates of