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?:abstract
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The coronavirus disease pandemic (coronavirus disease 2019 – COVID-19) has spread all over the world With the tendency towards stabilization of the incidence rate in some European countries, the number of patients being hospitalized remains significant The disease can be asymptomatic, however, the most dangerous manifestations are acute respiratory distress syndrome and fulminant pneumonia, which are most often the causes of death More and more information is appearing in the press about the involvement of the cardiovascular system in the pathological process, both in persons, who previously suffered from circulatory system diseases and in patients, who had no cardiovascular pathology before they became infected with COVID-19 Possible mechanisms of the damaging effects of SARS-CoV-2 on the cardiovascular system are increasingly discussed However, the accumulated data is not yet enough to draw global conclusions New information appears almost every day It was systematized in this review The focus is on the damaging effects of SARS-CoV-2 on the heart Methods Literary data were searched using PubMed and Google search among Russian-language and English-language original articles, recommendations of national professional communities, expert comments published since the beginning of the COVID-19 pandemic When searching, the terms “coronavirus”, “cardiac”, “cardiovascular”, “myocardial injury”, “myocardial infarction”, “troponin”, “myocarditis” were used Conclusion Currently, the mechanisms of heart damage with COVID-19 require further research The question remains what prevails: the specific, typical only for the SARS-CoV-2 virus, action on the heart, blood vessels, and hemostasis, or changes in the cardiovascular system are non-specific, inherent in the presence of a systemic inflammatory reaction and acute respiratory distress syndrome Preliminary evidence suggests that acute myocardial damage, accompanied by the increase of cardiac troponins, is by no means a rare condition associated with SARS-CoV-2 virus infection The presence of acute myocardial damage with any mechanism of its development contributes to increase of nosocomial mortality, regardless of the presence of cardiovascular diseases before the development of COVID-19 © 2020, Professionalnye Izdaniya All rights reserved
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