PropertyValue
?:abstract
  • Macrophages (Mø) are immune cells with natural phagocytic ability and play an important role in tumorigenesis, development and metastasis. Mø play a dual role of tumor inhibition and tumor promotion in tumor development due to their two different phenotypes. Mø in the tumor microenvironment have long been referred to as tumor-associated Mø (TAMs). Mø are mainly involved in tumor resistance, cancer metastasis and mediating immuno suppression. Nowadays, Mø and Mø membrane have been widely used in drug delivery systems (DDS) because of their good biocompatibility, natural phagocytosis, and their important role in tumor development. In this review, from the perspective of Mø\'s role in tumor development, we present strategies and drugs of Mø targeting and focus on the several types of biomimetic nanoparticles constructed by Mø and Mø membrane in tumor therapy, and discuss the problem of this delivery system in present research and future directions.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.1080/1061186x.2020.1775236
?:journal
  • Journal_of_drug_targeting
?:license
  • unk
?:pmid
?:pmid
  • 32603199.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • Medline
?:title
  • How to use macrophages to realize the treatment of tumor.
?:type
?:year
  • 2020-06-30

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