PropertyValue
?:abstract
  • Cytokine storm seems to be one of the main culprits for developing a severe form of COVID-19, IL-6 being one of its basic components Therefore, currently, tocilizumab is widely studied as a powerful treatment in patients with severe forms of COVID-19 Our aim was to determine whether it could potentiate a favourable outcome in such patients We conducted a retrospective observational study including all consecutive admitted patients with confirmed SARS-CoV-2 infection that received treatment with tocilizumab in the period between 01 05-23 08 2020 in Matei Bals National Institute for Infectious Diseases and Neurology Department of the Colentina Clinical Hospital in Bucharest, Romania 22 patients were enrolled with a severe form of COVID-19, predominantly women, with an average age of of 61 72 ± 14 5 years The fatality rate was 31 81% It was observed that following tocilizumab administration, patients presented improvement in the majority of the studied parameters, statistically significant in the case of fibrinogen, C reactive protein and blood oxygen level (p < 0 05) Tocilizumab might be regarded as a valuable drug in the management of severe SARS-CoV-2 infection © 2020, Romanian Society for Pharmaceutical Sciences All rights reserved
is ?:annotates of
?:creator
?:journal
  • Farmacia
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Influence of tocilizumab on the outcome of patients with covid-19. Retrospective observational study
?:type
?:who_covidence_id
  • #914997
?:year
  • 2020

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