PropertyValue
?:abstract
  • The novel and highly pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has become a continued focus of global attention due to the serious threat it poses to public health. There are no specific drugs available to combat SARS-CoV-2 infection. Natural products (carolacton, homoharringtonine, emetine, and cepharanthine) and natural product-inspired small molecules (ivermectin, GS-5734, EIDD-2801, and ebselen) are potential anti-SARS-CoV-2 agents that have attracted significant attention due to their broad-spectrum antiviral activities. Here, we review the research on potential landmark anti-SARS-CoV-2 agents, systematically discussing the importance of natural products and natural-product-inspired small molecules in the research and development of safe and effective antiviral agents.
?:creator
?:doi
?:doi
  • 10.3389/fphar.2020.01013
?:journal
  • Front_Pharmacol
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/9cb16a2d846811e1b55d528006621d622573bffa.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7343773.xml.json
?:pmcid
?:pmid
?:pmid
  • 32714193.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection
?:type
?:year
  • 2020-07-02

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