|
?:abstract
|
-
OBJECTIVE: A higher body mass index (BMI) has become acknowledged as one of the important risk factors for developing critical condition in coronavirus disease 2019 (COVID-19). In addition to BMI, body composition, particularly visceral adiposity, might be an even more accurate measure to stratify patients. Therefore, we aimed to evaluate the association between the distributions of CT-quantified fat mass and critical condition of patients with COVID-19. METHODS: A systematic search was conducted in five databases for studies published until 17th November 2020. In the meta-analysis, we calculated pooled mean difference (standardized mean difference; SMD) of visceral fat area (VFA; cm2 ) between patients in intensive care unit (ICU) and general ward, and between patients with and without IMV requirement. RESULTS: Our quantitative synthesis revealed that patients requiring intensive care had higher VFA values (SMD=0.46, 95% CI: 0.20, 0.71, p<0.001) compared to patients on the general ward. Similarly, patients requiring IMV had higher VFA values (SMD=0.38, 95% CI: 0.05, 0.71, p=0.026) compared to patients without IMV requirement. CONCLUSIONS: We found that VFA values were significantly higher in patients with critical condition. Therefore, abdominal adiposity seems to be a risk factor in COVID-19, and patients with central obesity might need special attention.
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}