xssmot

Property	Value
?:abstract	A virus is an infectious particle which generally contains nucleic acid genome (DNA or RNA inside a protein shell), except for human immunodeficiency virus (HIV). Viruses have to reproduce by infecting their host cells. Polyamines are ubiquitous compounds in mammalian cells and play key roles in various cellular processes. The metabolic pathways of polyamines have been well studied. Targeting these metabolic pathways can reduce infections caused by viruses. In the study, we systematically reviewed the association of polyamine metabolic pathways and viruses including coxsackievirus B3 (CVB3), enterovirus 71 (EV71), poliovirus (PV), Zika virus (ZKV), hepatitis C virus (HCV), hepatitis B virus (HBV), dengue virus (DENV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), Ebola virus (EBOV), marburgvirus (MARV), chikungunya virus (CHIKV), sindbis virus (SINV), Semliki Forest virus (SFV), Epstein–Barr virus (EBV), herpes simplex virus 1 (HSV), human cytomegalovirus (HCMV), vesicular stomatitis virus (VSV), Rabies virus (RABV), Rift Valley fever virus (RVFV), La Crosse virus (LACV), human immunodeficiency virus (HIV), Middle East respiratory syndrome virus (MERS-CoV), and coronavirus disease 2019 (SARS-CoV-2). This review revealed that targeting polyamine metabolic pathways may be a potential approach to control human viral infection.
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?:creator	<https://research.tib.eu/covid-19/entity/Huang%2C_Mingyuan%3B_Zhang%2C_Weijian%3B_Chen%2C_Haiyong%3B_Zeng%2C_Jincheng>
?:doi	<https://research.tib.eu/covid-19/entity/10.2147/idr.s262024>
?:doi	10.2147/idr.s262024
?:journal	Infect_Drug_Resist
?:license	cc-by-nc
?:pdf_json_files	document_parses/pdf_json/31f3b54302127d258151927a89bfd4add7bb7be8.json
?:pmc_json_files	document_parses/pmc_json/PMC7718961.xml.json
?:pmcid	<https://research.tib.eu/covid-19/entity/PMC7718961>
?:pmid	<https://research.tib.eu/covid-19/entity/33293837.0>
?:pmid	33293837.0
?:publication_isRelatedTo_Disease	<https://research.tib.eu/covid-19/entity/COVID-19>
is ?:relation_isRelatedTo_publication of	<https://research.tib.eu/covid-19/entity/85xssmot_HAS_C0042776_CAUSES_C3714514>
?:sha_id	<https://research.tib.eu/covid-19/entity/31f3b54302127d258151927a89bfd4add7bb7be8>
?:source	Medline; PMC
?:title	Targeting Polyamine Metabolism for Control of Human Viral Diseases
?:type	<https://research.tib.eu/covid-19/vocab/Publication>
?:year	2020-12-01

Property

Value

?:abstract

A virus is an infectious particle which generally contains nucleic acid genome (DNA or RNA inside a protein shell), except for human immunodeficiency virus (HIV). Viruses have to reproduce by infecting their host cells. Polyamines are ubiquitous compounds in mammalian cells and play key roles in various cellular processes. The metabolic pathways of polyamines have been well studied. Targeting these metabolic pathways can reduce infections caused by viruses. In the study, we systematically reviewed the association of polyamine metabolic pathways and viruses including coxsackievirus B3 (CVB3), enterovirus 71 (EV71), poliovirus (PV), Zika virus (ZKV), hepatitis C virus (HCV), hepatitis B virus (HBV), dengue virus (DENV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), Ebola virus (EBOV), marburgvirus (MARV), chikungunya virus (CHIKV), sindbis virus (SINV), Semliki Forest virus (SFV), Epstein–Barr virus (EBV), herpes simplex virus 1 (HSV), human cytomegalovirus (HCMV), vesicular stomatitis virus (VSV), Rabies virus (RABV), Rift Valley fever virus (RVFV), La Crosse virus (LACV), human immunodeficiency virus (HIV), Middle East respiratory syndrome virus (MERS-CoV), and coronavirus disease 2019 (SARS-CoV-2). This review revealed that targeting polyamine metabolic pathways may be a potential approach to control human viral infection.

is ?:annotates of