?:abstract
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Although high mortality has been reported in many COVID-19 studies, very limited postmortem information from complete autopsies is available We report the findings in the adrenal glands in 28 autopsies with confirmed SARS-CoV-2 infection Microscopic lesions were identified in the adrenal glands in 12/28 patients (46%) Seven cases showed necrosis, generally ischemic;four showed cortical lipid degeneration;two showed hemorrhage;and one unspecific focal adrenalitis Vascular thrombosis in one patient and focal inflammation in association with other findings in three patients were observed No case presented adrenal insufficiency In conclusion, adrenal lesions are frequent in patients with severe COVID-19 The lesions are mild but could contribute to the lethal outcome
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