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?:abstract
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Background: Quality of life (QOL) is an important outcome in ischaemic heart disease (IHD) We wished to examine the contribution of both socioeconomic deprivation and physical fitness, both potentially modifiable factors, to QOL in patients undergoing ischaemic stress testing Method: Patients presenting for exercise stress echocardiography (ESE) were invited to complete questionnaires, including the WHO Well-being Index (a QOL measure) Socioeconomic deprivation was measured by NZiDep, which asks participants whether they experience any of 8 features of deprivation We used a dichotomised score of no features of deprivation vs any Physical fitness was measured by treadmill exercise time achieved (Bruce protocol) Results: 73 patients were recruited, of whom five did not undergo exercise testing, leaving 68 in the cohort: mean age 66 years, 55% female, 90% NZ European 17% had ESE positive for ischaemia There was no difference in exercise time or rate of positive ESE between NZiDep groups In univariate regression, exercise time was positively associated with QOL (standardised ß=0 264) and NZiDep negatively associated (ß=-0 348) Other significant univariate factors were age, BMI, and NYHA class Sex and LVEF were not associated with QOL In linear multiple regression, NZiDep retained significance after the addition age and of exercise to the model After the addition of BMI, only exercise time remained significant Conclusion: Socioeconomic deprivation is significantly negatively associated with QOL, but this is not independent of BMI and exercise time In patients being investigated for myocardial ischaemia, interventions to improve physical capacity should be considered as targets for improving QOL
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