PropertyValue
?:abstract
  • OBJECTIVES: This study investigated demographics, comorbidities, and death rate in hospitalized patients with confirmed COVID-19. In addition, we hypothesized that functional status, according to the Clinical Frailty Scale (CFS), in patients aged 65 years or older is a better predictor of poor outcome than age and comorbidities. METHODS: A total of 255 randomly selected COVID-19 patients admitted to a university hospital were included and followed up for 60 days. Patient data were extracted manually from the electronic health records with use of a standardized protocol. RESULTS: The age of the study population ranged between 20 and 103 years (mean age 66 years ± 17 years). Hypertension, diabetes mellitus, and obesity were the three most prevalent comorbidities. At the 60-day follow-up, 70 patients (27%) had died. In multivariate analyses, age, chronic kidney disease, and previous stroke were associated with death. Most fatal cases (90%) occurred in patients aged 65 years or older. Among such patients, CFS level was the only predictor of death in multivariate analyses. CONCLUSIONS: This study shows that increasing age, chronic kidney disease, and previous stroke significantly contribute to a fatal outcome in hospitalized patients with COVID-19. In patients aged 65 years or older, CFS level was the strongest prognostic factor for death.
is ?:annotates of
?:creator
?:doi
  • 10.1016/j.ijid.2020.10.071
?:doi
?:journal
  • Int_J_Infect_Dis
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/bf29ec86862cdc6ad23fce7d0a8dd263ad6f4bf0.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7833745.xml.json
?:pmcid
?:pmid
?:pmid
  • 33130213.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Elsevier; Medline; PMC
?:title
  • Risk factors for death in adult COVID-19 patients: Frailty predicts fatal outcome in older patients
?:type
?:year
  • 2020-10-30

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