PropertyValue
?:definition
  • Tissue sealants comprised of two components, fibrinogen and thrombin. When the two components are combined, thrombin converts fibrinogen into fibrin monomers, which polymerizes to form a mechanical barrier. The fibrinogen component of these products is typically derived from human plasma (either pooled plasma or individual plasma units). The thrombin component may be derived from human or animal (e.g., bovine) origin. Fibrinogen/thrombin sealants (also known as fibrin sealant or fibrin glue) are available as separate preparations of fibrinogen from pooled human plasma and thrombin that are mixed at the time of application; as preparations of fibrinogen from pooled human plasma and thrombin that are fixed within an absorbable patch; and as kits that allow collection of fibrinogen from single-patient, which is then combined with a preparation of collagen and thrombin. Because fibrin and thrombin play direct role in the coagulation cascade and because of fibrin/thrombin sealant\'s glue-like properties, some forms of fibrinogen/thrombin sealant may be used as hemostats or adhesives in certain applications.
?:hasCUIAnnotation
?:hasGeneratedBy
?:type

Metadata

Anon_0  
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/net/provenance/ns#DataItem>
<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2004/03/trix/rdfg-1/Graph>
<http://xmlns.com/foaf/0.1/primaryTopic> <https://research.tib.eu/covid-19/entity/C0016004_UMD>
<http://xmlns.com/foaf/0.1/topic> Anon_0
<http://www.ontologydesignpatterns.org/cp/owl/informationrealization.owl#realizes> <https://research.tib.eu/covid-19/data/entity/C0016004_UMD>
<http://purl.org/net/provenance/ns#createdBy>
Anon_1   (more)
expand all